Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.6
USERS' SCORE
Moderately Good
Based on 49 Reviews
7.8
Supplement Facts
Serving Size: 1 Chewable Tablet
Serving Per Container: 120
Amount Per Serving
%DV
Melatonin
5 mg
†
Top Medical Research Studies
9.5
Melatonin improves sleep apnea outcomes
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
Read More
7
We conducted a study to see if agomelatine, a melatonin-based drug, could help patients with obstructive sleep apnea (OSA). In this randomized and single-blind trial, seventy adults took either agomelatine or a placebo for three nights before sleep testing.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
Read More
7
We explored how melatonin, known for its anti-inflammatory properties, interacts with obstructive sleep apnea (OSA) and related health issues.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
Read More
Most Useful Reviews
9
Effective for travel
5 people found this helpful
An excellent dosage for normalising sleep. I only use it as needed, like during flights or when overly excited after work, and it guarantees a wonderful night's sleep. I take 1 tablet half an hour before bed and wake up feeling refreshed and invigorated. Crucially, I have not experienced any addiction.
Read More
9
Swift sleep onset
4 people found this helpful
I can't let go of this melatonin! My sleep has improved significantly as I approach menopause. It's effective, and I often fall asleep within 10 minutes of taking it.
Read More
9
Enhanced evening routine
4 people found this helpful
With this supplement, my sleep has vastly improved. One tablet 15 minutes before bedtime suffices. I also take magnesium citrate and glycine in the evening, ensuring complete darkness and silence in my bedroom. This small tablet, with a pleasant mint taste, works wonders from the very first dose, evoking bright dreams.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7.6
- All Researches
9.5
Melatonin improves sleep apnea outcomes
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
Read More
7
We explored how melatonin, known for its anti-inflammatory properties, interacts with obstructive sleep apnea (OSA) and related health issues.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
Read More
7
We conducted a study to see if agomelatine, a melatonin-based drug, could help patients with obstructive sleep apnea (OSA). In this randomized and single-blind trial, seventy adults took either agomelatine or a placebo for three nights before sleep testing.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
Read More
7
We explored REM sleep behavior disorder (RBD) as a complex condition that can be linked to a variety of underlying disorders. Through a literature review and insights from foundational texts, we recognized that RBD may emerge at any age and can initially appear as an isolated issue or be associated with other significant conditions like Parkinson’s and narcolepsy.
Our findings highlighted that effective management often includes melatonin or clonazepam as treatment options. Furthermore, ongoing research into the connections between RBD and other sleep disorders, such as obstructive sleep apnea, remains vital for enhancing diagnostics and treatment strategies.
Our findings highlighted that effective management often includes melatonin or clonazepam as treatment options. Furthermore, ongoing research into the connections between RBD and other sleep disorders, such as obstructive sleep apnea, remains vital for enhancing diagnostics and treatment strategies.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 49 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective for travel
5 people found this helpful
An excellent dosage for normalising sleep. I only use it as needed, like during flights or when overly excited after work, and it guarantees a wonderful night's sleep. I take 1 tablet half an hour before bed and wake up feeling refreshed and invigorated. Crucially, I have not experienced any addiction.
Read More
9
Swift sleep onset
4 people found this helpful
I can't let go of this melatonin! My sleep has improved significantly as I approach menopause. It's effective, and I often fall asleep within 10 minutes of taking it.
Read More
9
Enhanced evening routine
4 people found this helpful
With this supplement, my sleep has vastly improved. One tablet 15 minutes before bedtime suffices. I also take magnesium citrate and glycine in the evening, ensuring complete darkness and silence in my bedroom. This small tablet, with a pleasant mint taste, works wonders from the very first dose, evoking bright dreams.
Read More
9
Deep restful sleep
3 people found this helpful
This is the best product I’ve ever used. My sleep quality has improved incredibly—I now take three of these nightly and enjoy deep, uninterrupted sleep without any groggy aftermath in the morning.
Read More
9
Combines well with 5HTP
3 people found this helpful
Melatonin combined with 5HTP is the only regimen that helps me sleep soundly. I take it before bed, and after years of trial and error with various supplements, this combination is the only one that ensures I fall and stay asleep.
Read More
Frequently Asked Questions
9
Swift sleep onset
4 people found this helpful
I can't let go of this melatonin! My sleep has improved significantly as I approach menopause. It's effective, and I often fall asleep within 10 minutes of taking it.
9
Enhanced evening routine
4 people found this helpful
With this supplement, my sleep has vastly improved. One tablet 15 minutes before bedtime suffices. I also take magnesium citrate and glycine in the evening, ensuring complete darkness and silence in my bedroom. This small tablet, with a pleasant mint taste, works wonders from the very first dose, evoking bright dreams.
7.5
Effective sleep aid
1 people found this helpful
These actually work! Very tiny chewable tablets with a mint flavour. They usually make me feel sleepy within the next hour. It’s best to pair them with good sleep hygiene: dimming the lights, turning off electronics, etc.
9
Effective for travel
5 people found this helpful
An excellent dosage for normalising sleep. I only use it as needed, like during flights or when overly excited after work, and it guarantees a wonderful night's sleep. I take 1 tablet half an hour before bed and wake up feeling refreshed and invigorated. Crucially, I have not experienced any addiction.
9
Deep restful sleep
3 people found this helpful
This is the best product I’ve ever used. My sleep quality has improved incredibly—I now take three of these nightly and enjoy deep, uninterrupted sleep without any groggy aftermath in the morning.
9
Quality sleep aid
The Melatonin Natural Mint 5 mg tablets stand out in quality. They are consistent and easy to manage. Users have noted significant improvements in their sleep patterns, with easier sleep onset and fewer disturbances during the night. The natural mint taste is pleasant and does not overpower, enhancing the experience. The sturdy packaging also ensures longevity.
0
Ineffective treatment
1 people found this helpful
This did not help me sleep at all. Our bodies produce melatonin after sundown, but it doesn’t necessarily lead to better sleep. It might make you feel tired but will not aid in sleeping.
9
Combines well with 5HTP
3 people found this helpful
Melatonin combined with 5HTP is the only regimen that helps me sleep soundly. I take it before bed, and after years of trial and error with various supplements, this combination is the only one that ensures I fall and stay asleep.
9.5
Melatonin improves sleep apnea outcomes
We investigated how melatonin affects patients with obstructive sleep apnea and insomnia. In a double-blind trial, thirty patients received either 10 mg of melatonin or a placebo for a month.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
The results were striking; those taking melatonin reported better sleep quality, less daytime sleepiness, and greater adherence to their PAP devices. Improvements were noted across several assessments: the Pittsburgh Sleep Quality Index, Insomnia Severity Index, Epworth Sleepiness Scale, and Functional Outcomes of Sleep Questionnaire showed significant gains for the melatonin group.
Thus, melatonin appears to be a promising option to enhance sleep quality and treatment compliance in this challenging patient group.
7
We explored how melatonin, known for its anti-inflammatory properties, interacts with obstructive sleep apnea (OSA) and related health issues.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
In a study of 235 men experiencing sleep problems, we found that higher OSA severity correlated with lower melatonin levels and increased markers of intestinal barrier dysfunction and inflammation.
Melatonin appeared to mediate these relationships, explaining a significant portion of the connection between apnea severity and these harmful conditions. However, the overall results suggest that while melatonin is connected to inflammation and intestinal issues in OSA, it does not appear to solve these complications.
7
We conducted a study to see if agomelatine, a melatonin-based drug, could help patients with obstructive sleep apnea (OSA). In this randomized and single-blind trial, seventy adults took either agomelatine or a placebo for three nights before sleep testing.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
The results showed that agomelatine improved total sleep time, sleep efficiency, and reduced waking percentage compared to the control group. However, other sleep parameters did not show significant changes. Overall, agomelatine may be beneficial for those struggling with OSA.
References
- Wei Z, Shen H, Wang F, Huang W, Li X, et al. Melatonin mediates intestinal barrier dysfunction and systemic inflammation in moderate-severe OSA patients. Ann Med. 2024;56:2361825. doi:10.1080/07853890.2024.2361825
- Motlaq TM, Rahimi B, Amini S. Effect of melatonin on insomnia and daytime sleepiness, in patients with obstructive sleep apnea and insomnia (COMISA): A randomized double-blinded placebo-controlled trial. J Pharm Health Care Sci. 2024;10:25. doi:10.1186/s40780-024-00347-9
- Dastan F, Gholizadeh Niari B, Adimi Naghan P, Barati S, Eskandari R. Evaluating the Effects of Agomelatine on Polysomnography Parameters in Patients with Obstructive Sleep Apnea. J Pharm Pharm Sci. 2023;25:418. doi:10.18433/jpps33252
- Schenck CH. REM sleep behavior disorder as a complex condition with heterogeneous underlying disorders: clinical management and prognostic implications [Commentary]. Sleep Breath. 2022;26:1289. doi:10.1007/s11325-022-02574-6
